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Description
The G46-6 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen. HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells: B cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.
Specifications
Specifications
| Antigen | HLA-DR |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | G46-6 |
| Conjugate | Brilliant Violet 711 |
| Description | MHC class II antigen; HLA class II histocompatibility antigen |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
| Quantity | 50 Tests |
| Regulatory Status | RUO |
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