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HLA-DR, DP, DQ Mouse anti-Human, FITC, Clone: Tu39 (also known as TÜ39), BD

Catalog No. BDB562008 Shop All BD Biosciences Products
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BDB562008 25 Tests
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Catalog No. BDB562008 Supplier BD Biosciences Supplier No. 562008
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Description

Mouse Monoclonal Antibody

The TU39 monoclonal antibody specifically recognizes human major histocompatibility (MHC) Class II HLA-DR, DP and most DQ antigens. These antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. MHC Class II antigens are transmembrane heterodimeric glycoproteins composed of α chain (36 kDa) and β chain (27 kDa) subunits. They are expressed primarily on antigen presenting cells which include dendritic cells, monocytes, macrophages, thymic epithelial cells, and B cells. They are also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4+ T lineage cells. The TU39 antibody is reportedly useful for immunophenotyping as well as functional studies including the inhibition of mixed lymphocyte reactions and antibody-mediated complement fixation on target cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen HLA-DR, DP, DQ
Applications Flow Cytometry
Classification Monoclonal
Clone Tu39 (also known as TÜ39)
Conjugate FITC
Description Tü39
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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