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HLA-DR Mouse anti-Human, PE-Cy5, Clone: G46-6, BD

Catalog No. BDB562007 Shop All BD Biosciences Products
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BDB562007 25 Tests
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Catalog No. BDB562007 Supplier BD Biosciences Supplier No. 562007
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Description

Mouse Monoclonal Antibody

The G46-6 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen. HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells: B cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen HLA-DR
Applications Flow Cytometry
Classification Monoclonal
Clone G46-6
Conjugate PE-Cyanine5
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Baboon, Canine, Cynomolgus, Human, Rhesus Monkey
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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