MilliporeSigma™ anti-Hsp47 Clone: M16.10A1,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ 38602350UG

Catalog No. 38-602-350UG

Description

Specifically detects Hsp47 Clone: M16.10A1 in Bovine, Canine, Chicken, Guinea Pig, Hamster, Human, Monkey, Mouse, Porcine, Rat, Sheep samples, and it is validated for ELISA, Enzyme Immunoassay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Immuno Blotting

Hsp47 is a unique heat shock protein with collagen binding ability. A member of the serpin family of proteins, Hsp47 localizes within the ER due to an RDEL sequence, a variant of the KDEL sequence. Hsp47 is thought to bind procollagen immediately after it co-translationally enters the ER, and it dissociates from procollagen before its secretion. The ability of Hsp47 to bind collagen I and collagen IV suggests it may function as a molecular chaperone for these proteins.

Specifications

• Antigen: Hsp47
• Classification: Monoclonal
• Conjugate: Unconjugated
• Host Species: Mouse
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Bovine, Canine, Chicken, Guinea Pig, Hamster, Human, Monkey, Mouse, Pig, Rat, Sheep
• Form: Purified

• Applications: ELISA, Immunoblot, Immunoblot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
• Clone: M16.10A1
• Formulation: In PBS, 50% glycerol, pH 7.2.
• Immunogen: Hsp47 from L6 cells
• Regulatory Status: RUO
• Test Specificity: Recognizes the ∽47kDa Hsp47 protein.
• Content And Storage: −20°C
• Isotype: IgG2b

For Research Use Only