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HSPB8, Mouse, Clone: 5G3, Abnova™

Mouse monoclonal antibody raised against a partial recombinant HSPB8.

Manufacturer:  Abnova Corporation H00026353M05

Catalog No. 89-002-611


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Description

Description

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq

Sequence: KVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGESSFNNELPQDSQEVTCT
Specifications

Specifications

HSPB8
5G3
Mouse monoclonal antibody raised against a partial recombinant HSPB8.
HSPB8
Liquid
HSPB8
HSPB8 (NP_055180, 97 a.a. ~ 196 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
100 ug
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
ELISA, Western Blot
Unconjugated
In 1X PBS, pH 7.4
NM_014365
CMT2L|DHMN2|E2IG1|H11|HMN2|HMN2A|HSP22
Mouse
IgG3 Kappa
RUO
Primary
26353
Documents
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