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CD2 Mouse anti-Human, Brilliant Violet 605, Clone: RPA-2.10, BD

Catalog No. BDB562667 Shop All BD Biosciences Products
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Catalog No. BDB562667 Supplier BD Biosciences Supplier No. 562667
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Description

Mouse Monoclonal Antibody

The RPA-2.10 monoclonal antibody specifically binds to CD2. CD2 is a 50 kDa single-chain transmembrane glycoprotein, also known as LFA-2 or the receptor for sheep erythrocytes. CD2 belongs to the immunoglobulin superfamily of proteins along with its ligand LFA-3, CD58. It is present on about 80-90% of human peripheral blood lymphocytes, greater than 95% of thymocytes, all T lymphocytes that form E-rosettes and a subset of NK cells. CD2 plays a role in T-cell signaling and in lymphocyte adhesion.

The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon™ BV421can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon™ BV421conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD2
Applications Flow Cytometry
Classification Monoclonal
Clone RPA-2.10
Conjugate Brilliant Violet 605
Description LFA-2; Lymphocyte function antigen-2; T11/Leu-5; Rosette receptor
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Phytohemagglutinin-treated Lymphoblasts
Purification Method Affinity Purified
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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