TRA-1-60 Mouse anti-Human, Brilliant Violet 421, Clone: TRA-1-60, BD

Catalog No.	Quantity
BDB562711	50 Tests

Catalog No. BDB562711 Supplier BD Biosciences Supplier No. 562711

Description

Mouse Monoclonal Antibody

The TRA-1-60 monoclonal antibody reacts with the neuraminidase-resistant form of a pluripotent-stem-cell-specific epitope on a high-molecular-weight transmembrane glycoprotein. The TRA-1-60 antigen is a sialylated epitope on the same keratan sulfate core molecule, podocalyxin, as 4 other distinct antigens on tumor-derived cell lines, TRA-1-81, GCTM2, K4, and K21. The expression of TRA-1-60 antigen is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. The antigen is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (but not morula or trophoblast), and embryonic stem (ES) cells. TRA-1-60 antigen is released into the serum of patients bearing testicular tumors containing EC cells. As human EC and ES cells undergo differentiation, expression of TRA-1-60 antigen is lost. Expression of TRA-1-60 antigen has also been observed on a rhesus monkey ES cell line (Thomson et al, 1995).

Host Species: Mouse
Clone: TRA-1-60
Isotype: IgM, κ
Species Reactivity: Hu

Flow Cytometry

Specifications

• Antigen: TRA-1-60
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: TRA-1-60
• Conjugate: Brilliant Violet 421
• Description: TRA-1-60(R)
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Host Species: Mouse
• Immunogen: Human Embryonal Carcinoma Cell Line
• Purification Method: Affinity Purified
• Quantity: 50 Tests
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgM κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov