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HVEM (CD270) Mouse anti-Human, Alexa Fluor 647, Clone: 94801, BD

Catalog No. BDB564411 Shop All BD Biosciences Products
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Catalog No. BDB564411 Supplier BD Biosciences Supplier No. 564411
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Description

Mouse Monoclonal Antibody

The 94801 monoclonal antibody specifically binds to HVEM (Herpes virus entry mediator). HVEM is also known as CD270 and LIGHT Receptor (LIGHT-R). CD270 is a type I transmembrane protein and member of the TNF Receptor superfamily. It is encoded by TNFRSF14 (tumor necrosis factor receptor superfamily member 14). CD270 is expressed on resting T cells, B cells, monocytes, and some dendritic cells. CD270 binds to homotrimeric Lymphotoxin α (LTa3/ TNFβ ), LIGHT (is homologous to lymphotoxins, exhibits inducible expression, and competes with HSV glycoprotein D for HVEM, a receptor expressed by T lymphocytes), CD272/BTLA, and glycoprotein D of Herpes simplex viruses HSV-1 and HSV-2. CD270-LIGHT interactions can reportedly transduce costimulatory signals for T cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen HVEM (CD270)
Applications Flow Cytometry
Classification Monoclonal
Clone 94801
Conjugate Alexa Fluor 647
Description LIGHT-R; HVEA; HVEM; TNFRSF14; TR2
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human HVEM Recombinant Protein
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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