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I-Ak Mouse anti-Mouse, FITC, Clone: 10-3.6, BD

Catalog No. BDB562014 Shop All BD Biosciences Products
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BDB562014 50 μg
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Catalog No. BDB562014 Supplier BD Biosciences Supplier No. 562014
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Mouse Monoclonal Antibody

The 10-3.6 antibody reacts with the β chain of the I-A[k] MHC class II alloantigen. It cross-reacts with splenocytes from mice of the H-2[f], H-2[r], and H-2[s] haplotypes, from nonobese diabetic (NOD, H-2[g7]) mice, and with lymph node cells of BN, DA, WRA, and WRC rats. Reactivity with other haplotypes (e.g., b, d, p, q) has not been observed. Long-term in vivo treatment with 10-3.6 mAb has been reported to prevent the spontaneous development of autoimmune insulin-dependent diabetes mellitus (IDDM) in female NOD mice.

TRUSTED_SUSTAINABILITY

Specifications

Antigen I-Ak
Applications Flow Cytometry
Classification Monoclonal
Clone 10-3.6
Concentration 0.5mg/mL
Conjugate FITC
Description Aβk
Formulation Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species Mouse
Immunogen C3H mouse splenocytes
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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