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ID3 Mouse, PE, Clone: S30-778, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 564564

Catalog No. BDB564564


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Description

Description

The S30-778 monoclonal antibody specifically binds to Inhibitor of DNA binding 3 (ID3). ID3 is one of four ID proteins (ID1-4) that have been characterized in humans. It is also known as Class B basic helix-loop-helix protein 25 (BHLHB25), Helix-loop-helix protein HEIR-1, and ID-like protein inhibitor HLH 1R21. ID3 is a Helix-Loop-Helix (HLH) protein that can form heterodimers with other HLH transcription factors such as MyoD, myogenin, E12 and E47. These latter transcription factors normally regulate the development, differentiation and functions of a variety of cell types including muscle cells, and subsets of T and B cells. Because it lacks a basic DNA-binding domain, ID3 can inhibit the DNA binding and function of these other transcription factors it complexes with. Abnormal ID3 expression has been associated with certain cancers. The S30-778.8.66 antibody crossreacts with mouse Id3.

Specifications

Specifications

ID3
S30-778
PE
Aqueous buffered solution containing ≤0.09% sodium azide.
Murine
IgG1, κ
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.2mg/mL
ID-3; Inhibitor of DNA binding 3; 1R21; BHLHB25; HEIR1; HEIR-1
Affinity Purified
Human ID3 Recombinant Protein
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
RUO
Primary
Human, Murine
Documents
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