isocitrate dehydrogenase 2 (NADP+), mitochondrial, Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a partial recombinant IDH2.
Manufacturer: Abnova Corporation H00003418A01
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeqSequence: HYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR
|isocitrate dehydrogenase 2 (NADP+), mitochondrial|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|ELISA, Western Blot|
|Mouse polyclonal antibody raised against a partial recombinant IDH2.|
|IDH2 (NP_002159, 354 a.a. ~ 451 a.a) partial recombinant protein with GST tag.|
|This antibody cross-reacts with human IDH1.|
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