IFN-α (2b) Mouse anti-Human, NA/LE, Unlabeled, Clone: 7N4-1, BD

Catalog No.	Quantity
BDB551795	0.5 mg

Catalog No. BDB551795 Supplier BD Biosciences Supplier No. 551795

Description

Mouse Monoclonal Antibody

The 7N4-1 antibody reacts with human IFN-α2b and to a lesser extent with IFN-α7. It does not react with IFN-α1 nor IFN-α4. IFN-α2b is one of the three variants of IFN-α2 that have been isolated from human cell lines. IFN-α2b is the variant predominantly produced by human leukocytes. Human IFN-α2b belongs to the IFN-α class of proteins also known as leukocyte interferons. IFN-α comprises a family of related but distinct proteins with molecular weights ranging from 16-27kDa with antiviral, antiproliferative and immunomodulatory activities. The IFN-α family is composed from as many as 14 different genes. The immunogen used to generate the 7N4-1 hybridoma was E. coli-expressed recombinant human IFN-α2b. This is a neutralizing antibody.

Host Species: Mouse
Clone: 7N4-1
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: E. coli-expressed recombinant human IFN-α2b

Functional Assay, Immunohistochemistry

Specifications

• Antigen: IFN-α (2b)
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: 7N4-1
• Concentration: 1.0mg/mL
• Conjugate: Unconjugated
• Description: IFNa, IFNα
• Formulation: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
• Host Species: Mouse
• Immunogen: E. coli-expressed recombinant human IFN-α2b
• Purification Method: Affinity Purified
• Quantity: 0.5 mg
• Regulatory Status: RUO
• Research Discipline: Immunology
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Store undiluted at 4°C
• Isotype: IgG1 κ

For Research Use Only.