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IFN-Gamma Rat anti-Mouse, Brilliant Violet 650, Clone: XMG1.2, BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 563854

Catalog No. BDB563854


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Description

Description

The XMG1.2 monoclonal antibody specifically binds to mouse interferon- γ(IFN- γ) protein. IFN- γis a pleiotropic cytokine, of approximately 15-17 kDa, involved in the regulation of inflammatory and immune responses. It plays an important role in activation, growth, and differentiation of T and B lymphocytes, macrophages, NK cells and other non-hematopoietic cell types. IFN- γproduction is associated with the Th1 cell differentiation. The purified form of this antibody has been reported to be a neutralizing antibody.

The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. This dye is a tandem fluorochrome of BD Horizon™ BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 650-nm. BD Horizon™ BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20-nm filter). Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors. However, the spillover can be corrected through compensation as with any other dye combination.

Specifications

Specifications

IFN-Gamma
XMG1.2
Brilliant Violet 650
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Rat
IgG1, κ
RUO
Primary
Murine
Flow Cytometry
0.2mg/mL
IFN-γ; IFN-g; IFN-gamma; Interferon gamma; Type II Interferon
Affinity Purified
Mouse IFN-Gamma Recombinant Protein
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
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