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IFN-γ Mouse anti-Human, FITC, Clone: 4S.B3, BD

Catalog No. BDB561057 Shop All BD Biosciences Products
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BDB561057 25 μg
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Catalog No. BDB561057 Supplier BD Biosciences Supplier No. 561057
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Description

Mouse Monoclonal Antibody

The 4S.B3 monoclonal antibody specifically binds to interferon-γ(IFN-γ). The immunogen used to generate this hybridoma was partially purified human IFN-γobtained from supernatants of human PBMC stimulated with Staphylococcus aureus . Interferon-γ(IFN-γ) is a potent multifunctional cytokine that is produced by several activated cell types including NK, NKT, CD4+TCRαβ+, CD8+TCRαβ+, and TCRγδ + T cells. IFN- γexerts its biological effects through specific binding to the high-affinity IFN-γReceptor Complex comprised of IFN-γRα (CD119) and ese influences can involve IFN- γ’s capacity to boost MHC class I and II expression by antigen-presenting cells as well as to direct effects on B cells and T cells themselves. Human IFN-γis a 14- 18 kDa glycoprotein containing 143 amino acid residues.

TRUSTED_SUSTAINABILITY

Specifications

Antigen IFN-γ
Applications Flow Cytometry
Classification Monoclonal
Clone 4S.B3
Concentration 0.5mg/mL
Conjugate FITC
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human IFN-γ from supernatants of S. aureus-stimulated PBMC
Purification Method Affinity Purified
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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