IL-11 Mouse anti-Human, Clone: 22616, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523711
This antibody shows 100% cross-reactivity with recombit mouse IL-11 but does not cross-react with recombit human (rh) IL-6, rhIL-6 R, rhLIF, rhOSM, rhCT-1, rhCNTF, or rhCLC. Reconstitute at 0.5 mg/mL in sterile PBS.Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production.Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.
|PBS with 5% trehalose and No Preservative|
|Interleukin-11, Interleukin11, Interleukin 11, IL-11, Adipogenesis inhibitory factor, AGIF, INN=Oprelvekin, IL11|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|Sf 21-derived recombit human IL-11 Pro22-Leu199|
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