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IL-11 Mouse anti-Human, Clone: 22616, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523711

Catalog No. PIMA523711


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Description

Description

This antibody shows 100% cross-reactivity with recombit mouse IL-11 but does not cross-react with recombit human (rh) IL-6, rhIL-6 R, rhLIF, rhOSM, rhCT-1, rhCNTF, or rhCLC. Reconstitute at 0.5 mg/mL in sterile PBS.

Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production.Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.
Specifications

Specifications

IL-11
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P20809
Interleukin-11, Interleukin11, Interleukin 11, IL-11, Adipogenesis inhibitory factor, AGIF, INN=Oprelvekin, IL11
Mouse
IgG2b
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
3589
ELISA, Western Blot
22616
Unconjugated
IL11
Lyophilized
IL11
Sf 21-derived recombit human IL-11 Pro22-Leu199
Protein A/G
RUO
Antibody
Monoclonal
Human
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