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Description
The C15.6 monoclonal antibody specifically binds to both free and complexed (homodimer p80 and heterodimer p70) forms of the p40 subunit of mouse interleukin-12 (IL-12). The immunogen used to generate the C15.6 hybridoma was recombinant mouse IL-12 p70 protein. p40 has also been described as a subunit of IL-23 and thus it is possible that the C15.6 antibody will crossreact with IL-23.
The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences. It is excited by the Violet laser Ex max of 406nm and has an Em Max at 450 nm. Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.
Specifications
Specifications
| Antigen | IL-12 (p40/p70) |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | C15.6 |
| Concentration | 0.2mg/mL |
| Conjugate | Violet Fluor 450 (V450) |
| Description | IL-12/IL-23 p40; Il12b; Interleukin 12b; CLMF p40 |
| Formulation | Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | CHO-expressed recombinant mouse IL-12 p70 protein |
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