IL-13 Rat anti-Mouse, Clone: 38213, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA523735
In ELISAs, this antibody shows less than 0.1% cross-reactivity with recombit human IL-13. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
|PBS with 5% trehalose and No Preservative|
|ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600, interleukin-13|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Neutralization, Western Blot|
|E. coli-derived recombit mouse IL-13|
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