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  6. IL-17A Rat anti-Mouse, Alexa Fluor 647, Clone: TC11-18H10, BD

IL-17A Rat anti-Mouse, Alexa Fluor 647, Clone: TC11-18H10, BD

Catalog No. BDB560184 Shop All BD Biosciences Products
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25 μg
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BDB560184 0.1 mg
BDB560224 25 μg
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Catalog No. BDB560184 Supplier BD Biosciences Supplier No. 560184
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Description

Rat Monoclonal Antibody

The TC11-18H10 antibody reacts with recombinant and natural mouse IL-17A proteins. IL-17A, also known as CTLA-8, is a T cell-derived cytokine that promotes inflammatory responses. Mouse IL-17A is a proinflammatory cytokine that can induce the release of IL-6 by mouse stromal cells. It has been shown to support the growth of hemopoietic progenitors in vitro; it can also stimulate granulopoiesis in vivo. The TC11-18H10 antibody has been reported to neutralize IL-17A activity. Recent studies have shown that IL-17A is produced by a unique subset of Th17 cells that develop along a pathway distinct from the Th1- and Th2- cell differentiation pathways. The mouse IL-17A cDNA was isolated from a cDNA library generated from TCRαβ+CD4-CD8- thymocytes.

Host Species: Rat
Clone: TC11-18H10
Isotype: IgG1 κ
Species Reactivity: Mouse
Immunogen: Recombinant Mouse IL-17A Protein

Intracellular Staining

TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-17A
Applications Flow Cytometry
Classification Monoclonal
Clone TC11-18H10
Concentration 0.2mg/mL
Conjugate Alexa Fluor 647
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Recombinant Mouse IL-17 Protein
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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