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  6. IL-17A Rat anti-Mouse, Unlabeled, Clone: TC11-18H10, BD

IL-17A Rat anti-Mouse, Unlabeled, Clone: TC11-18H10, BD

Catalog No. BDB559501 Shop All BD Biosciences Products
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BDB559501 0.1 mg
BDB555068 0.5 mg
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Description

Rat Monoclonal Antibody

The TC11-18H10 antibody reacts with recombinant and natural mouse IL-17A proteins. IL-17A, also known as CTLA-8, is a T cell-derived cytokine that promotes inflammatory responses. Mouse IL-17A is a proinflammatory cytokine that can induce the release of IL-6 by mouse stromal cells. It has been shown to support the growth of hemopoietic progenitors in vitro; it can also stimulate granulopoiesis in vivo. The TC11-18H10 antibody has been reported to neutralize IL-17A activity. Recent studies have shown that IL-17A is produced by a unique subset of Th17 cells that develop along a pathway distinct from the Th1- and Th2- cell differentiation pathways. The mouse IL-17A cDNA was isolated from a cDNA library generated from TCRαβ+CD4-CD8-thymocytes.

Blocking Assay, ELISA, Intracellular Staining, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-17A
Applications Blocking Assay, ELISA, Flow Cytometry
Classification Monoclonal
Clone TC11-18H10
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Recombinant Mouse IL-17 Protein
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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For Research Use Only.

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