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IL-17 A/F Rat anti-Mouse, Clone: 50104, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA523748

Catalog No. PIMA523748


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Description

Description

In direct ELISAs, approximately 40% reactivity with recombit mouse (rm) IL-17A/IL-17F heterodimer is observed. No cross-reactivity with recombit human IL-17, recombit canine IL-17, rmIL-17B, rmIL-17C, rmIL-17D, rmIL-17E, or rmIL-17F is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Specifications

Specifications

IL-17 A/F
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q62386, Q7TNI7
Il17a, IL17F, Interleukin-17A, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, IL17A, CTLA8, IL17, Interleukin-17F, IL-17F, Cytokine ML-1
Rat
IgG2a
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
16171, 257630
Neutralization, Western Blot
50104
Unconjugated
Il17f
Lyophilized
IL17A, IL17F
E. coli-derived recombit mouse IL-17 Thr22-Ala158
Protein A/G
RUO
Antibody
Monoclonal
Mouse
Documents
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