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IL-21 Receptor Rat anti-Mouse, PE, Clone: 4A9, BD

Catalog No. BDB558607 Shop All BD Biosciences Products
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BDB558607 0.1 mg
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Catalog No. BDB558607 Supplier BD Biosciences Supplier No. 558607
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Description

Rat Monoclonal Antibody

The rat monoclonal antibody 4A9 recognizes the mouse IL-21 receptor (IL-21R), a member of the cytokine receptor superfamily that closely resembles IL-2Rβ and IL-4Rα. The functional IL-21R, consisting of the IL-21R subunit and the common γ-chain, activates Jak-1, Jak-3, STAT1, STAT3, and STAT5 by binding the ligand, IL-21. The cellular response to ligand binding is complex being dependent on co-stimulation with other molecules and can result in either positive or negative regulatory signals . IL-21R is detected on developing T and B lymphocytes after commitment to each of these lineages with highest expression on mature and activated T and B lymphocytes. It has also been found to be involved in NK cell expansion.

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-21 Receptor
Applications Flow Cytometry
Classification Monoclonal
Clone 4A9
Concentration 0.2mg/mL
Conjugate PE
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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