IL-4 Mouse anti-Human, Clone: 3010, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523692
In sandwich ELISAs, no cross-reactivity or interference was observed with recombit human (rh) IL-1 alpha, rhIL-1 beta, rhIL-2, rhIL-3, rhIL-6, rhIL-7, rhIL-8, rhG-CSF, rhGM-CSF, rhTNF-alpha, rhTNF- beta, rhLIF, rhTGF- beta 1, recombit mouse (rm) IL-1 beta, rmIL-6, rmIL-7, rmGM-CSF, bovine FGF acidic, bovine FGF basic, porcine PDGF, human TGF- beta 1, porcine TGF- beta 1.2, and porcine TGF- beta 2. Reconstitute at 0.5 mg/mL in sterile PBS.Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
|PBS with 5% trehalose and No Preservative|
|B cell growth factor 1, BSF-1, B_cell stimulatory factor 1, binetrakin, interleukin-4, lymphocyte stimulatory factor 1, pitrakinra|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|E. coli-derived recombit human IL-4 His25-Ser153|
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