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IL-9 Armenian Hamster anti-Mouse, PerCP-Cy5.5, Clone: D9302C12, BD

Catalog No. BDB561492 Shop All BD Biosciences Products
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BDB561492 50 μg
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Catalog No. BDB561492 Supplier BD Biosciences Supplier No. 561492

Description

Armenian Hamster Monoclonal Antibody

The D9302C12 monoclonal antibody specifically binds to the multifunctional mouse cytokine, Interleukin-9 (IL-9). IL-9 is a 126 amino acid-long glycoprotein that is produced by various subsets of activated CD4+ T cells. IL-9 acts on target cells by binding to and signaling through the heterodimeric IL-9 receptor (IL-9R) complex that is comprised of transmembrane IL-9 receptor alpha (IL-9R α) and common gamma chain (γc) subunits. IL-9 can promote the survival, growth, proliferation and/or differentiation of various cell types including thymocytes, T cells, B cells, mast cells, and hematopoietic progenitor cells. IL-9 can augment IL-4-induced IgE and IgG1 production from lipopolysaccharide-primed mouse B cells and induce granzyme and high-affinity IgE receptor gene expression by mouse T helper cell clones and mast cell lines. IL-9 plays an important role in vivo in helminth elimination. The D9302C12 antibody neutralizes mouse IL-9 bioactivity.

TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-9
Applications Flow Cytometry
Classification Monoclonal
Clone D9302C12
Concentration 0.2mg/mL
Conjugate PerCP-Cyanine5.5
Description IL-9; Interleukin-9; MEA; P40; T-cell growth factor P40; TCGF III
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Armenian Hamster
Immunogen Mouse IL-9 Recombinant Protein
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2 κ
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