interleukin 13, Mouse, Clone: 7E4, Abnova™

Catalog No.	Quantity
89-000-752	100 μg

Catalog No. 89-000-752 Supplier Abnova Corporation Supplier No. H00003596M01

Description

Mouse monoclonal antibody raised against a full-length recombinant IL13.

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq

Specifications

• Antigen: interleukin 13
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 7E4
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a full length recombinant IL13.
• Formulation: PBS with no preservative; pH 7.4
• Gene: IL13
• Gene Accession No.: P35225
• Gene Alias: ALRH/BHR1/IL-13/MGC116786/MGC116788/MGC116789/P600
• Gene Symbols: IL13
• Host Species: Mouse
• Immunogen: IL13 recombinant protein.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Whole Molecule: Yes
• Primary or Secondary: Primary
• Gene ID (Entrez): 3596
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Isotype: IgG2a κ