ILT5 (CD85a) Mouse anti-Human, Alexa Fluor 647, Clone: 222821, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 564469
The 222821 monoclonal antibody specifically binds to Immunoglobulin-like transcript 5 (ILT5) which is also known as CD85a (CD85 antigen-like family member A), Leukocyte immunoglobulin-like receptor 3 (LIR-3), and Monocyte inhibitory receptor HL9. ILT5 is encoded by LILRB3 and belongs to the ILT/LTR family in the Ig gene superfamily. ILT5 is expressed by a variety of cell types including monocytes, macrophages, granulocytes, NK cells, osteoclast precursors, and a subset of T lymphocytes. This transmembrane receptor contains intracellular immunoreceptor tyrosine based inhibitory motifs (ITIMs) that can inhibit intracellular signaling. ILT5 can bind to MHC Class I molecules and appears to be involved in regulating immune responses such as NK cell-mediated cytotoxicity.
|LILRB3; HL9; LIR3; LIR-3; PIRB; PIR-B; ILT-5|
|Human ILT5 Recombinant Protein|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
|Alexa Fluor 647|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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