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ILT5 (CD85a) Mouse anti-Human, Alexa Fluor 647, Clone: 222821, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 564469

Catalog No. BDB564469


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Description

Description

The 222821 monoclonal antibody specifically binds to Immunoglobulin-like transcript 5 (ILT5) which is also known as CD85a (CD85 antigen-like family member A), Leukocyte immunoglobulin-like receptor 3 (LIR-3), and Monocyte inhibitory receptor HL9. ILT5 is encoded by LILRB3 and belongs to the ILT/LTR family in the Ig gene superfamily. ILT5 is expressed by a variety of cell types including monocytes, macrophages, granulocytes, NK cells, osteoclast precursors, and a subset of T lymphocytes. This transmembrane receptor contains intracellular immunoreceptor tyrosine based inhibitory motifs (ITIMs) that can inhibit intracellular signaling. ILT5 can bind to MHC Class I molecules and appears to be involved in regulating immune responses such as NK cell-mediated cytotoxicity.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

ILT5 (CD85a)
Monoclonal
Alexa Fluor 647
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Human ILT5 Recombinant Protein
50 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
222821
LILRB3; HL9; LIR3; LIR-3; PIRB; PIR-B; ILT-5
Mouse
Affinity Purified
RUO
Human
IgG2a κ
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