Learn More
ILT5 (CD85a) Mouse anti-Human, Alexa Fluor 647, Clone: 222821, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 564469
Description
The 222821 monoclonal antibody specifically binds to Immunoglobulin-like transcript 5 (ILT5) which is also known as CD85a (CD85 antigen-like family member A), Leukocyte immunoglobulin-like receptor 3 (LIR-3), and Monocyte inhibitory receptor HL9. ILT5 is encoded by LILRB3 and belongs to the ILT/LTR family in the Ig gene superfamily. ILT5 is expressed by a variety of cell types including monocytes, macrophages, granulocytes, NK cells, osteoclast precursors, and a subset of T lymphocytes. This transmembrane receptor contains intracellular immunoreceptor tyrosine based inhibitory motifs (ITIMs) that can inhibit intracellular signaling. ILT5 can bind to MHC Class I molecules and appears to be involved in regulating immune responses such as NK cell-mediated cytotoxicity.

Specifications
ILT5 (CD85a) | |
Monoclonal | |
Alexa Fluor 647 | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Human ILT5 Recombinant Protein | |
50 Tests | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Flow Cytometry | |
222821 | |
LILRB3; HL9; LIR3; LIR-3; PIRB; PIR-B; ILT-5 | |
Mouse | |
Affinity Purified | |
RUO | |
Human | |
IgG2a κ |
Your input is important to us. Please complete this form to provide feedback related to the content on this product.