ILT5 (CD85a) Mouse anti-Human, Alexa Fluor 647, Clone: 222821, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 564469

Catalog No. BDB564469

Description

The 222821 monoclonal antibody specifically binds to Immunoglobulin-like transcript 5 (ILT5) which is also known as CD85a (CD85 antigen-like family member A), Leukocyte immunoglobulin-like receptor 3 (LIR-3), and Monocyte inhibitory receptor HL9. ILT5 is encoded by LILRB3 and belongs to the ILT/LTR family in the Ig gene superfamily. ILT5 is expressed by a variety of cell types including monocytes, macrophages, granulocytes, NK cells, osteoclast precursors, and a subset of T lymphocytes. This transmembrane receptor contains intracellular immunoreceptor tyrosine based inhibitory motifs (ITIMs) that can inhibit intracellular signaling. ILT5 can bind to MHC Class I molecules and appears to be involved in regulating immune responses such as NK cell-mediated cytotoxicity.

Specifications

• Antigen: ILT5 (CD85a)
• Clone: 222821
• Description: LILRB3; HL9; LIR3; LIR-3; PIRB; PIR-B; ILT-5
• Format: Affinity Purified
• Immunogen: Human ILT5 Recombinant Protein
• Purification Method: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human

• Applications: Flow Cytometry
• Conjugate: Alexa Fluor 647
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Host Species: Murine
• Isotype: IgG_2a, κ
• Quantity: 50 Tests
• Storage Requirements: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Monoclonal or Polyclonal: Monoclonal