INS, Mouse, Clone: 7C8, Abnova™

Catalog No.	Quantity
89-123-198	100 μg

Catalog No. 89-123-198 Supplier Abnova Corporation Supplier No. H00003630M02

Description

Mouse monoclonal antibody raised against a KLH-conjugated peptide spanning 48 - 62 amino acid sequence of human Proinsulin.

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq]

Sequence: CFFYTPKTRREAEDLQ

Specifications

• Antigen: INS
• Applications: ELISA
• Classification: Monoclonal
• Clone: 7C8
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a KLH-conjugated peptide spanning 48 ∼ 62 amino acid sequence of human Proinsulin.
• Formulation: PBS with no preservative; pH 7.4
• Gene: INS
• Gene Accession No.: NM_000207
• Gene Alias: ILPR/IRDN
• Gene Symbols: INS
• Host Species: Mouse
• Immunogen: KLH-conjugated human Proinsulin peptide (NP_000198, 48 a.a. ∼ 62 a.a)
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3630
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG3 κ