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INSRR Mouse anti-Human, Clone: 326929, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524051

Catalog No. PIMA524051


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Description

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Specifications

Specifications

INSRR
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P14616
insulin receptor-related receptor
Mouse
IgG2B
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
3645
Flow Cytometry, Western Blot
326929
Unconjugated
INSRR
Lyophilized
INSRR
Mouse myeloma cell line NS0-derived recombit human INSRR Leu24-Leu923
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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