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Integrin β7 Rat, Brilliant Violet 421, Clone: FIB504, BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 564283

Catalog No. BDB564283


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Description

Description

FIB504 reacts with mouse integrin β 7 subunit (130 kD) but also cross reacts with human integrin β 7. Integrin β 7 associates with α 4 (CD49d) expressed on subsets of lymphocytes and thymus. It also associates with α IEL (CD103) expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Integrin β 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.

The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Specifications

Specifications

Integrin β7
FIB504
Itgb7; Integrin β7; Integrin beta 7; ITB7; Ly-69; Ly69
Affinity Purified
Mouse T lymphoma line TK1
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
Brilliant Violet 421
Aqueous buffered solution containing BSA and ≤0.09% sodium azide
Rat
IgG2b, κ
RUO
Primary
Human, Murine
Documents
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