Integrin β7 Rat, Brilliant Violet 421, Clone: FIB504, BD
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 564283
FIB504 reacts with mouse integrin β 7 subunit (130 kD) but also cross reacts with human integrin β 7. Integrin β 7 associates with α 4 (CD49d) expressed on subsets of lymphocytes and thymus. It also associates with α IEL (CD103) expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Integrin β 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.
|Itgb7; Integrin β7; Integrin beta 7; ITB7; Ly-69; Ly69|
|Mouse T lymphoma line TK1|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Brilliant Violet 421|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok