Integrin β7 Chain Rat anti-Mouse, NA/LE, Unlabeled, Clone: FIB27, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 553812

Catalog No. BDB553812

Description

The FIB27 antibody reacts with the integrin β7 chain (also known as integrin βp), which is found in association with either of two α chains. α4β7 (LPAM-1) is expressed on most mature lymphocytes and on small subsets of thymic and bone marrow cells; it interacts with several ligands, including VCAM-1, fibronectin, and MAdCAM-1. αIELβ7 is found primarily on intestinal intraepithelial lymphocytes (IEL), and it may be involved in interactions between IEL and epithelia via recognition of E-cadherin. The FIB27 antibody blocks β7 integrin-mediated adhesion to fibronectin, MAdCAM-1, and VCAM-1, and it cross-reacts with human integrin β7.

Host Species: Rat
Clone: FIB27
Isotype: IgG2a κ
Species Reactivity: Mouse
Immunogen: AKR/Cum mouse spontaneous T lymphoma cell line TK1

Blocking Assay, Flow Cytometry

Specifications

• Antigen: Integrin β7 Chain
• Classification: Monoclonal
• Concentration: 1.0mg/mL
• Formulation: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
• Immunogen: AKR/Cum mouse spontaneous T lymphoma cell line TK1
• Quantity: 0.5 mg
• Research Discipline: Immunology
• Target Species: Human, Mouse
• Isotype: IgG2a κ

• Applications: Flow Cytometry
• Clone: FIB27
• Conjugate: Unconjugated
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

For Research Use Only.