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MilliporeSigma™ anti-Integrin alphaIIb Clone: 283.16B7,

Catalog No. 407313100UL Shop All MilliporeSigma Products
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Quantity:
100 μL
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
40-731-3100UL 100 μL Unconjugated
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Catalog No. 40-731-3100UL Supplier MilliporeSigma™ Supplier No. 407313100UL
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Mouse Monoclonal Antibody

Specifically detects Integrin αIIb Clone: 283.16B7 in Human samples, and it is validated for ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)

The integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated α and β subunits. CD41 consists of two disulfide-linked subunits, GPIIba and GPIIbb. CD41 non-covalently associates with CD61 (integrin β3) and is expressed by megakaryocytes and platelets. The CD41/CD61 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Integrin αIIb
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 283.16B7
Conjugate Unconjugated
Formulation Undiluted ascites.
Host Species Mouse
Immunogen integrin αIIb from M21-L-llb melanoma cells
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Recognizes the αIIb integrin chain. Antibody Target Gene Symbol: ITGA2B Target Synonym: AI172977, ALPHA 2B, alphaIIb, CD41, CD41A, CD41B, GP2B, GPIIB, GTA, HPA3, INTEGRIN ALPHA 2B, Itga2b, LOC685269 Entrez Gene Name: integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Target Species Human
Content And Storage −20°C
Form Ascites
Isotype IgG1
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