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Integrin beta 7 Mouse anti-Human, FITC, Clone: 473207, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523592

Catalog No. PIMA523592


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Description

Description

In Western blots, no cross-reactivity with recombit human Integrin beta 1, beta 2, beta 3, beta 4, beta 5, beta 6, beta 8, recombit mouse Integrin beta 4, or beta 7 is observed.

Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
Specifications

Specifications

Integrin beta 7
Monoclonal
FITC
ITGB7
Liquid
ITGB7
CHO-derived recombit human Integrin beta 7 long isoform Glu20-His723
Protein A/G
RUO
Antibody
Monoclonal
Human
Flow Cytometry
473207
Buffered saline solution with BSA and 0.09% sodium azide
P26010
Integrin beta-7, Gut homing receptor beta subunit, ITGB7
Mouse
IgG1
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
3695
Documents
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