Islet-1 Mouse, Unlabeled, Clone: Q11-465, BD

Catalog No.	Quantity
BDB562546	0.1 mg

Catalog No. BDB562546 Supplier BD Biosciences Supplier No. 562546

Description

Mouse Monoclonal Antibody

Islet-1 is a LIM-homeodomain transcription factor important for motor neuron differentiation and the formation of islet cells in the pancreas. Various heart cell types, such as cardiac muscle, the conduction system and endothelial cells in multiple heart tissue compartments during cardiogenesis, have been found to originate from Islet-1-positive cardiac precursor cells. Moreover, Islet-1-positive cells from differentiated human embryonic stem cell lines were found to be capable of self-renewal and expansion and could differentiate into the three major cell types of the heart. Western blot analyses of lysates from transfected cells demonstrate that the Q11-465 monoclonal antibody reacts with human Islet-1 and Islet-2, similar to the 4D5 clone (Tsuchida et al, 1994). Cross-reactivity with mouse Islet is also observed.

• Alternate Name: ISL-1, ISL1, Islet-2, ISL-2, ISL2
• Isotype: IgG1, κ
• Host Species: Mouse
• Cross Reactivity: Mouse, Human
• Immunogen: Human Islet-1 Recombinant Protein
• Target MW: 45-50kDa
• Unlabeled

Western Blotting, Bioimaging, Immunofluorescence, Intracellular Staining (Flow Cytometry)

Specifications

• Antigen: Islet-1
• Applications: Western Blot
• Classification: Monoclonal
• Clone: Q11-465
• Concentration: 0.5mg/mL
• Conjugate: Unconjugated
• Description: ISL-1, ISL1, Islet-2, ISL-2, ISL2
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Host Species: Mouse
• Immunogen: Human Islet-1 Recombinant Protein
• Purification Method: Affinity Purified
• Quantity: 0.1 mg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Content And Storage: Store undiluted at 4°C
• Isotype: IgG1 κ