Ki-67 Mouse, Alexa Fluor 647, Clone: B56, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 558615

Catalog No. BDB558615

Description

The B56 monoclonal antibody reacts with the Ki-67 antigen, which is expressed in the nucleus of cycling cells. During G0 phase, the antigen cannot be detected. During interphase of the cell cycle, it is associated with nucleolar components, and it is on the surface of the chromosomes during M phase. Ki-67 is a large protein having 2 alternatively spliced isoforms, an N-terminal forkhead-associated domain, a C-terminal domain that binds to heterochromatin proteins, and multiple phosphorylation sites, the functions of which are still unclear. Because of the strict association of Ki-67 expression with cell proliferation, anti-Ki-67 antibodies are useful for the identification, quantification, and monitoring of growing cell populations.

Intracellular Staining

Specifications

• Antigen: Ki-67
• Classification: Monoclonal
• Conjugate: Alexa Fluor 647
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: Human Ki-67
• Quantity: 100 Tests
• Research Discipline: Cell Biology
• Target Species: Human, Mouse, Rat, Rhesus Monkey
• Isotype: IgG1 κ

• Applications: In vitro Assay
• Clone: B56
• Description: MKI67; Antigen identified by monoclonal antibody Ki-67; KIA
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov