killer cell lectin-like receptor subfamily C, member 1, Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a partial recombinant KLRC1.
Manufacturer: Abnova Corporation H00003821A01
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeqSequence: MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQGNDKTYHCKDLPSAPEK
|killer cell lectin-like receptor subfamily C, member 1|
|ELISA, Western Blot|
|Mouse polyclonal antibody raised against a partial recombinant KLRC1.|
|KLRC1 (NP_998823, 1 a.a. ~ 70 a.a) partial recombinant protein with GST tag.|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
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