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anti-LAMP1/CD107a, NL557, Clone: 508921, R&D Systems™

Catalog No. NL4800R
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0.5 mL
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NL4800R 0.5 mL
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Description

Lysosome-associated Membrane Glycoprotein 1

Lysosomal associated membrane protein 1 (LAMP1), also known as CD107a and LGP120, is an approximately 120 kDa transmembrane glycoprotein that is a major protein component of lysosomal membranes. In cytotoxic T cells and mast cells, LAMP1 is expressed in the membranes of intracellular granules that contain effector molecules such as perforin, granzymes, eicosanoids, and histamine. LAMP1 is presented on the plasma membrane during the activation of NK cells, CD8+ T cells, mast cells, basophils, monocytes, and platelets. A glycoform of LAMP1 known as M150 is expressed on the surface of activated macrophages where it promotes T cell costimulation and a Th1 biased immune response.

Host Species: Mouse
Clone: 508921
Isotype: IgG2B
Species Reactivity: Hu
Immunogen: NS0-derived recombinant human LAMP1 (Ala28-Asn380); Accession # P11279.

Applications:

Immunocytochemistry

Specifications

Antigen LAMP-1/CD107a
Applications Immunocytochemistry
Classification Monoclonal
Clone 508921
Conjugate NorthernLights 557 (NL557)
Dilution Immunocytochemistry
Formulation Supplied in a saline solution containing BSA and Sodium Azide. with Sodium Azide
Gene Accession No. P11279
Gene Alias CD107 antigen-like family member A, CD107a, CD107a antigen, LAMP1, LAMP-1, LAMPA, LGP120, lysosomal-associated membrane protein 1, lysosome-associated membrane glycoprotein 1, Lysosome-associated membrane protein 1
Gene Symbols LAMP1
Host Species Mouse
Immunogen NS0-derived recombinant human LAMP1 (Ala28-Asn380;; Accession # P11279).
Purification Method Protein A or G purified from hybridoma culture supernatant
Quantity 0.5 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3916
Target Species Human
Content And Storage Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Form Purified
Isotype IgG2b
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