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LAP Mouse anti-Human, PerCP-Cy5.5, Clone: TW4-2F8, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 562544
Description
The TW4-2F8 monoclonal antibody specifically binds to Latency-Associated Peptide (LAP), a component of the dimeric Transforming Growth Factor-beta 1 (TGF-β1) propeptide encoded by TGFB1. Prior to secretion, the dimeric LAP-TGF-β1 propeptide is cleaved resulting in a biologically inactive form of dimeric TGF-β1 that is noncovalently associated with dimeric LAP (latent TGF-β1). This complex may be expressed on the surface of TGF-β1TGF-β1. TGF-β1 is a potent multifunctional cytokine that regulates numerous processes including development, hematopoiesis, tissue remodeling, wound repair, and immunity as well as cancer and autoimmune diseases. Clone TW4-2F8 is routinely quality tested through intracellular staining of LAP in P3UI-TGFβ1 transfected cells.

Specifications
LAP | |
Monoclonal | |
PerCP-Cyanine5.5 | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Human TGF-β1 | |
50 Tests | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Flow Cytometry | |
TW4-2F8 | |
Latency-associated peptide; TGFB1; TGFbeta; Transforming growth factor beta | |
Mouse | |
Affinity Purified | |
RUO | |
Human | |
IgG1 κ |
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