LIM domain binding 3, Mouse, Clone: 3C8, Abnova™

Catalog No.	Quantity
89-001-524	200 μL

Catalog No. 89-001-524 Supplier Abnova Corporation Supplier No. H00011155M06A

Description

Mouse monoclonal antibody raised against a full-length recombinant LDB3.

This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1 and 2) have C-terminal LIM domains. [provided by RefSeq

Sequence: MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQERFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDFSGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRERFETERNSPRFAKLRNWHHGLSAQILNVKS

Specifications

• Antigen: LIM domain binding 3
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 3C8
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a full length recombinant LDB3.
• Formulation: ascites with no preservative
• Gene: LDB3
• Gene Accession No.: BC010929
• Gene Alias: CYPHER/FLJ35865/KIAA01613/KIAA0613/ORACLE/PDLIM6/ZASP/ldb3z1/ldb3z4
• Gene Symbols: LDB3
• Host Species: Mouse
• Immunogen: LDB3 (AAH10929, 1 a.a. ∼ 283 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 200 μL
• Regulatory Status: RUO
• Whole Molecule: Yes
• Primary or Secondary: Primary
• Gene ID (Entrez): 11155
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Ascites
• Isotype: IgG2b κ