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LDB3, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human LDB3 peptide using ARM Technology.

Supplier:  Abnova Corporation H00011155K

Catalog No. 89-210-650


Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

Description

This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1 and 2) have C-terminal LIM domains. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

  1. Customer may provide cell or tissue lysate for antibody screening.
  2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

Specifications

LDB3
Monoclonal
Unconjugated
In 1X PBS, pH 7.4
LDB3
LDB3
A synthetic peptide of human LDB3
RUO
11155
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
IgG
ELISA, Western Blot
1mg
LIM domain binding 3
LDB3
CYPHER, FLJ35865, KIAA01613, KIAA0613, ORACLE, PDLIM6, ZASP, ldb3z1, ldb3z4
Rabbit
1 mg x up to 3 Abs
Primary
Human
Liquid
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