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Leptin Receptor (CD295) Mouse anti-Human, Alexa Fluor 647, Clone: 52263, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 564376

Catalog No. BDB564376


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Description

Description

The 52263 monoclonal antibody specifically binds to the Leptin Receptor (Leptin R/LEPR) which is also known as CD295. CD295 is a type I transmembrane glycoprotein that belongs to the type I Cytokine Receptor family within the Immunoglobulin gene superfamily. Multiple isoforms of CD295 have been detected including a long form with a large cytoplasmic domain capable of signal transduction. Several receptor isoforms with short cytoplasmic domains that lack the capacity to transduce signals have also been reported. CD295 is widely expressed by a variety of cells within different tissues. CD295 binds to leptin with high affinity and plays important roles in lipid metabolism, fertility, angiogenesis, bone formation and immunity.

Specifications

Specifications

Leptin Receptor (CD295)
52263
LEPR; Leptin receptor; LEP-R; OB receptor; OBR; HuB219
Affinity Purified
Human Leptin Receptor Recombinant Protein
50 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
Alexa Fluor 647
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG2b, κ
RUO
Primary
Human
Documents
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