Leptin Receptor (CD295) Mouse anti-Human, Alexa Fluor 647, Clone: 52263, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 564376
The 52263 monoclonal antibody specifically binds to the Leptin Receptor (Leptin R/LEPR) which is also known as CD295. CD295 is a type I transmembrane glycoprotein that belongs to the type I Cytokine Receptor family within the Immunoglobulin gene superfamily. Multiple isoforms of CD295 have been detected including a long form with a large cytoplasmic domain capable of signal transduction. Several receptor isoforms with short cytoplasmic domains that lack the capacity to transduce signals have also been reported. CD295 is widely expressed by a variety of cells within different tissues. CD295 binds to leptin with high affinity and plays important roles in lipid metabolism, fertility, angiogenesis, bone formation and immunity.
|Leptin Receptor (CD295)|
|LEPR; Leptin receptor; LEP-R; OB receptor; OBR; HuB219|
|Human Leptin Receptor Recombinant Protein|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Alexa Fluor 647|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
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