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Leptin Receptor (CD295) Mouse anti-Human, Alexa Fluor 647, Clone: 52263, BD

Catalog No. BDB564376 Shop All BD Biosciences Products
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BDB564376 50 Tests
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Catalog No. BDB564376 Supplier BD Biosciences Supplier No. 564376
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Description

Mouse Monoclonal Antibody

The 52263 monoclonal antibody specifically binds to the Leptin Receptor (Leptin R/LEPR) which is also known as CD295. CD295 is a type I transmembrane glycoprotein that belongs to the type I Cytokine Receptor family within the Immunoglobulin gene superfamily. Multiple isoforms of CD295 have been detected including a long form with a large cytoplasmic domain capable of signal transduction. Several receptor isoforms with short cytoplasmic domains that lack the capacity to transduce signals have also been reported. CD295 is widely expressed by a variety of cells within different tissues. CD295 binds to leptin with high affinity and plays important roles in lipid metabolism, fertility, angiogenesis, bone formation and immunity.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Leptin Receptor (CD295)
Applications Flow Cytometry
Classification Monoclonal
Clone 52263
Conjugate Alexa Fluor 647
Description LEPR; Leptin receptor; LEP-R; OB receptor; OBR; HuB219
Host Species Mouse
Immunogen Human Leptin Receptor Recombinant Protein
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b κ
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