LIMK1, Mouse, Clone: 1A8, Abnova™
Mouse monoclonal antibody raised against a partial recombinant LIMK1.
Manufacturer: Abnova Corporation H00003984M01A
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. [provided by RefSeqSequence: ADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPD
|ascites with no preservative|
|Human, Murine, Rat|
|ELISA, Western Blot|
|Mouse monoclonal antibody raised against a partial recombinant LIMK1.|
|LIMK1 (NP_002305, 548 a.a. ∼ 647 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
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