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LPAM-1 Rat anti-Mouse, NA/LE, Unlabeled, Clone: DATK32, BD

Catalog No. BDB553809 Shop All BD Biosciences Products
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BDB553809 0.5 mg
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Catalog No. BDB553809 Supplier BD Biosciences Supplier No. 553809
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Description

Rat Monoclonal Antibody

The DATK32 antibody reacts with an epitope specific to the α4β7 integrin heterodimer. α4β7 (LPAM-1) is expressed on most mature lymphocytes and on small subsets of thymic and bone marrow cells. It interacts with several ligands, including VCAM-1 (CD106), fibronectin, and MAdCAM-1. DATK32 antibody induces α4β7-dependent lymphocyte aggregation, but it inhibits other α4β7- mediated lymphocyte adhesion events, including binding to fibronectin, MAdCAM-1, and VCAM-1 (CD106).

Host Species: Rat
Clone: DATK32
Isotype: IgG2a κ
Species Reactivity: Mouse
Immunogen: AKR/Cum mouse T lymphoma line TK1

Blocking Assay, Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen LPAM-1
Applications Flow Cytometry
Classification Monoclonal
Clone DATK32
Concentration 1.0mg/mL
Conjugate Unconjugated
Description Itga4Itgb7; α4β7 Integrin; alpha 4 beta 7 integrin; CD49dβ7
Formulation No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Host Species Rat
Immunogen AKR/Cum mouse T lymphoma line TK1
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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