LPAM-1 Rat anti-Mouse, PE, Clone: DATK32, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 553811

Catalog No. BDB553811

Description

The DATK32 antibody reacts with an epitope specific to the α4β7 integrin heterodimer. α4β7 (LPAM-1) is expressed on most mature lymphocytes and on small subsets of thymic and bone marrow cells. It interacts with several ligands, including VCAM-1 (CD106), fibronectin, and MAdCAM-1. DATK32 antibody induces α4β7-dependent lymphocyte aggregation, but it inhibits other α4β7- mediated lymphocyte adhesion events, including binding to fibronectin, MAdCAM-1, and VCAM-1 (CD106).

Host Species: Rat
Clone: DATK32
Isotype: IgG2a κ
Species Reactivity: Mouse
Immunogen: AKR/Cum mouse T lymphoma line TK1

Flow Cytometry

Specifications

• Antigen: LPAM-1
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: Itga4Itgb7; α4β7 Integrin; alpha 4 beta 7 integrin; CD49dβ7
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: DATK32
• Conjugate: PE
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: AKR/Cum mouse T lymphoma line TK1
• Quantity: 0.2 mg
• Research Discipline: Immunology
• Target Species: Mouse
• Isotype: IgG2a κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.