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Description
The DATK32 antibody reacts with an epitope specific to the α4β7 integrin heterodimer. α4β7 (LPAM-1) is expressed on most mature lymphocytes and on small subsets of thymic and bone marrow cells. It interacts with several ligands, including VCAM-1 (CD106), fibronectin, and MAdCAM-1. DATK32 antibody induces α4β7-dependent lymphocyte aggregation, but it inhibits other α4β7- mediated lymphocyte adhesion events, including binding to fibronectin, MAdCAM-1, and VCAM-1 (CD106).
Host Species: Rat
Clone: DATK32
Isotype: IgG2a κ
Species Reactivity: Mouse
Immunogen: AKR/Cum mouse T lymphoma line TK1
Flow Cytometry
Specifications
Specifications
| Antigen | LPAM-1 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | DATK32 |
| Concentration | 0.2mg/mL |
| Conjugate | PE |
| Description | Itga4Itgb7; α4β7 Integrin; alpha 4 beta 7 integrin; CD49dβ7 |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | AKR/Cum mouse T lymphoma line TK1 |
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Safety and Handling
For Research Use Only.
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