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Description
The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms
Specifications
Specifications
| Antigen | leupaxin |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Mouse polyclonal antibody raised against a full-length human LPXN protein. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | LPXN |
| Gene Accession No. | NM_004811.1 |
| Gene Alias | LDPL |
| Gene Symbols | LPXN |
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