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Ly-6C Rat anti-Mouse, APC-Cy7, Clone: AL-21, BD

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Catalog No. BDB560596 Supplier BD Biosciences Supplier No. 560596
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Description

Rat Monoclonal Antibody

The AL-21 antibody reacts with a non-polymorphic determinant of Ly-6C, a 14- 17kDa GPI-linked cell-surface antigen found on some monocyte/macrophage populations, granulocytes, endothelial cells, plasma cells, and thymocyte, NK-cell, and T-subsets. Mice with the Ly-6.2 alloantigen (eg, AKR, C57BL, C57BR, C57L, C58, DBA/2, PL, SJL, SWR, 129) have subsets of CD8+ and CD4+ Ly-6C+ T cells, while Ly-6.1 strains (eg, A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+ Ly-6C+ T cells. Upregulation of Ly-6C expression on CD8+ T cells by interferons α and β and poly (I:C) has been described, and Ly-6C is a memory marker on CD8+ T cells.

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen Ly-6C
Applications Flow Cytometry
Classification Monoclonal
Clone AL-21
Concentration 0.2mg/mL
Conjugate APC-Cyanine7
Description Ly6c; Lymphocyte antigen 6 complex, locus C; Lymphocyte antigen Ly-6C
Formulation Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species Rat
Immunogen Not reported
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgM κ
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