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Ly-6D Rat anti-Mouse, Alexa Fluor 647, Clone: 49-H4, BD

Catalog No. BDB561147 Shop All BD Biosciences Products
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BDB561147 0.05 mg
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Catalog No. BDB561147 Supplier BD Biosciences Supplier No. 561147

Rat Monoclonal Antibody

The 49-H4 antibody specifically binds to the ThB antigen (Ly-6D), which is a 15-kDa GPI-anchored protein of the Ly-6 Multigene Family. ThB has been detected on cortical thymocytes, small sIg- Thy-1- and sIg+ lymphoid cells in the bone marrow, thymic medullary epithelial cells, all epidermal layers (except the stratum corneum), and on peripheral B lymphocytes, but not on peripheral T lymphocytes. It has been noted that there is strain-to-strain variation in the expression of the ThB antigen on splenic B cells, those of strains with the Ly-6.2haplotype (e.g., AKR, C57BL, DBA/2, SJL, SWR) stain more intensely with anti-ThB reagents than those of Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, NZB), and B cells of hybrids of Ly-6.1 and Ly-6.2 strains stain with intermediate intensity. The proportions of the ThB+ B cells and thymocytes do not differ significantly among strains.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Ly-6D
Applications Flow Cytometry
Classification Monoclonal
Clone 49-H4
Concentration 0.2mg/mL
Conjugate Alexa Fluor 647
Description Lymphocyte antigen 6 complex, locus D; Thb; Thymocyte B-cell antigen; Ly-61
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen BALB/c mouse plasmacytoma MOPC-104E
Purification Method Affinity Purified
Quantity 0.05 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2c κ
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