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  6. Lyn Mouse, Unlabeled, Clone: 42, BD

Lyn Mouse, Unlabeled, Clone: 42, BD

Catalog No. BDB610003 Shop All BD Biosciences Products
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50 μg
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Catalog No. Quantity
BDB610003 50 μg
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Catalog No. BDB610003 Supplier BD Biosciences Supplier No. 610003

Description

Mouse Monoclonal Antibody

Lyn is a 56 kDa cytosolic tyrosine kinase that belongs to the Src family of kinases. In addition to Src, this family includes lck, Fgr, Hck, Blk, Yes, fyn, and Yrk kinases. The lyn gene was isolated from a human placenta cDNA library and later found in a variety of cell types. Similar to other members of the Src family of tyrosine kinases, Lyn has been implicated in the regulation of cell signaling mechanisms. Lyn's function has primarily been studied in hematopoietic cells where it is associated with the high-affinity IgE receptor in basophils. It also associates with p120 Ras-GAP in thrombin-stimulated platelets. This association corresponds to an increase in Lyn kinase activity. Lyn is often observed as a doublet of about 56 kDa and 53 kDa. These forms may represent alternative splicing products of lyn mRNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Lyn
Applications Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 42
Concentration 250μg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Lyn aa. 1-138
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Canine, Human, Mouse, Rat
Content And Storage Store undiluted at -20°C.
Isotype IgG1
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For Research Use Only.

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