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MilliporeSigma™ anti-MafK/Nfe2u, Polyclonal

Catalog No. ABE1928MI Shop All MilliporeSigma Products
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Quantity:
100 μL
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
ABE1928MI 100 μL Unconjugated
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Catalog No. ABE1928MI Supplier MilliporeSigma™ Supplier No. ABE1928
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Description

Rabbit Polyclonal Antibody

Specifically detects MafK/Nfe2u Clone: in Human, Mouse, Rat samples, and it is validated for ChIP, Chromatin Immunoprecipitation, Western Blotting

Transcription factor MafK (UniProt Q61827; also known as Erythroid transcription factor NF-E2 p18 subunit, Nuclear factor erythroid derived 2 ubiquitous, p18 NF-E2) is encoded by the Mafk (also known as Nfe2u, AW061068) gene (Gene ID 17135) in murine species. MafK, MafG and MafF consistute a family of transcription factors that dimerize with the CNC (cap' n' collar) family regulatory protein Nrf2 (NF-E2 p45-related factor 2) via their bZip domain. The Nrf2/small Maf heterodimer regulates downstream genes, including those of phase II detoxifying enzymes, by targeting antioxidant responsive element (ARE) and Maf recognition element (MARE).
TRUSTED_SUSTAINABILITY

Specifications

Antigen MafK/Nfe2u
Applications ChIP Assay, Western Blot, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation Rabbit polyclonal serum with 0.05% sodium azide.
Gene Accession No. Q61827
Gene Symbols Mafk, Nfe2u
Host Species Rabbit
Immunogen Maltose binding protein-tagged recombinant protein corresponding to mouse MafK/Nfe2u.
Purification Method Unpurified
Quantity 100 μL
Regulatory Status RUO
Research Discipline Epigenetics, Nuclear Function
Primary or Secondary Primary
Gene ID (Entrez) NP_034887
Target Species Human, Mouse, Rat
Content And Storage −20°C for one year
Form Serum
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For Research Use Only

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