MilliporeSigma™ anti-MafK/Nfe2u, Polyclonal

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ ABE1928

Catalog No. ABE1928MI

Description

Specifically detects MafK/Nfe2u Clone: in Human, Mouse, Rat samples, and it is validated for ChIP, Chromatin Immunoprecipitation, Western Blotting

Transcription factor MafK (UniProt Q61827; also known as Erythroid transcription factor NF-E2 p18 subunit, Nuclear factor erythroid derived 2 ubiquitous, p18 NF-E2) is encoded by the Mafk (also known as Nfe2u, AW061068) gene (Gene ID 17135) in murine species. MafK, MafG and MafF consistute a family of transcription factors that dimerize with the CNC (cap' n' collar) family regulatory protein Nrf2 (NF-E2 p45-related factor 2) via their bZip domain. The Nrf2/small Maf heterodimer regulates downstream genes, including those of phase II detoxifying enzymes, by targeting antioxidant responsive element (ARE) and Maf recognition element (MARE).

Specifications

• Antigen: MafK/Nfe2u
• Classification: Polyclonal
• Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
• Gene Symbols: Mafk, Nfe2u
• Immunogen: Maltose binding protein-tagged recombinant protein corresponding to mouse MafK/Nfe2u.
• Quantity: 100 μL
• Research Discipline: Epigenetics, Nuclear Function
• Gene ID (Entrez): NP_034887
• Content And Storage: −20°C for one year

• Applications: ChIP Assay, Western Blot, Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: Q61827
• Host Species: Rabbit
• Purification Method: Unpurified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Serum

For Research Use Only