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MilliporeSigma™ anti-MafK/Nfe2u, Polyclonal
Rabbit Polyclonal Antibody
Supplier: MilliporeSigma™ ABE1928
Description
Specifically detects MafK/Nfe2u Clone: in Human, Mouse, Rat samples, and it is validated for ChIP, Chromatin Immunoprecipitation, Western Blotting
Transcription factor MafK (UniProt Q61827; also known as Erythroid transcription factor NF-E2 p18 subunit, Nuclear factor erythroid derived 2 ubiquitous, p18 NF-E2) is encoded by the Mafk (also known as Nfe2u, AW061068) gene (Gene ID 17135) in murine species. MafK, MafG and MafF consistute a family of transcription factors that dimerize with the CNC (cap' n' collar) family regulatory protein Nrf2 (NF-E2 p45-related factor 2) via their bZip domain. The Nrf2/small Maf heterodimer regulates downstream genes, including those of phase II detoxifying enzymes, by targeting antioxidant responsive element (ARE) and Maf recognition element (MARE).
Specifications
MafK/Nfe2u | |
Polyclonal | |
Rabbit polyclonal serum with 0.05% sodium azide. | |
Mafk, Nfe2u | |
Maltose binding protein-tagged recombinant protein corresponding to mouse MafK/Nfe2u. | |
100 μL | |
Epigenetics, Nuclear Function | |
NP_034887 | |
−20°C for one year |
ChIP Assay, Western Blot, Western Blot | |
Unconjugated | |
Q61827 | |
Rabbit | |
Unpurified | |
RUO | |
Primary | |
Human, Mouse, Rat | |
Serum |
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