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Mast Cells Mouse anti-Rat, Unlabeled, Clone: AR32AA4, BD

Catalog No. BDB551770 Shop All BD Biosciences Products
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Catalog No. BDB551770 Supplier BD Biosciences Supplier No. 551770
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Description

Mouse Monoclonal Antibody

The AR32AA4 (AA4) antibody reacts with two distinct α-galactosyl derivatives of the ganglioside GD1b (disialogangliosides). The mAb AA4 reacts with four indistinct bands ranging in size from 56 - 110kDa. Binding of the AA4 antibody to RBL-2H3 cells has been shown to inhibit IgE-mediated histamine release by inhibiting FcεR1 signal transduction events. The mAb AA4 has been shown to be useful for immunomagnetic mast cell separation from rat bone marrow and peritoneal lavage cell populations. This corresponds with reports that the AA4-binding epitope is expressed at higher levels than the FcεR1 on RBL-2H3 cells.

Host Species: Mouse
Clone: AR32AA4 (also known as AA4)
Isotype: IgG1 κ
Species Reactivity: Rat
Immunogen: Rat basophilic leukemia cell line

Cell Separation, Flow Cytometry, Immunohistochemistry, Immunoprecipitation

TRUSTED_SUSTAINABILITY

Specifications

Antigen Mast Cells
Applications Flow Cytometry
Classification Monoclonal
Clone AR32AA4
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Rat basophilic leukemia cell line
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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For Research Use Only.

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