MCM3, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA121998

Catalog No. PIPA121998

Description

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.

PA1-21998 detects MCM3 in Human samples.PA1-21998 has been successfully used in Immunoprecipitation and Western Blot procedures.PA1-21998 immunogen corresponds to Synthetic peptide of 38 amino acids representing a portion of human MCM 3 encoded by exons 10 and 11.

Specifications

• Antigen: MCM3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: P25205, P25206
• Gene Symbols: MCM3
• Immunogen: Synthetic peptide of 38 amino acids representing a portion of human MCM 3 encoded by exons 10 and 11
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot
• Concentration: 1mg/mL
• Gene: MCM3
• Gene Alias: HCC5, MGC1157, P1-MCM3, P1.h, RLFB
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4172
• Content And Storage: Store at 4°C
• Form: Purified