MCOLN2, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human MCOLN2 peptide using ARM Technology.

Supplier:  Abnova Corporation H00255231K

Catalog No. 89-204-882

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 [PubMed 17662026]).[supplied by OMIM

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: MCOLN2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: MCOLN2
• Gene Symbols: MCOLN2
• Immunogen: A synthetic peptide of human MCOLN2
• Regulatory Status: RUO
• Gene ID (Entrez): 255231
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: mucolipin 2
• Gene: MCOLN2
• Gene Alias: FLJ36691, TRP-ML2, TRPML2
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid